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Cognitive and Emotional Health Project: The Healthy Brain







Self-Assessment of Memory (metamemory)

Asset & Health Dynamics among the Oldest Old (AHEAD; Herzog & Wallace 1997)

Items adapted from modified TICS:
o Immediate free recall. 10 short, concrete, high-frequency nouns were read to the respondent, who was then asked to recall as many of them as possible.
o Delayed free recall. After 5 minutes had passed, respondent was asked to recall the nouns previously presented.
o Serial 7s: Respondent asked to start at 100 & subtract by increments of 7 for 5 trials.
o Other tests: counting backward from 20 for 10 continuous answers; naming day of the week & date; naming objects that "people usually use to cut paper" & "the kind of prickly plant that grows in the desert"; naming president & vice-president.
o Similarities Test modified from WAIS-R
o Self-rated memory (metamemory)
o Herzog & Wallace (1997). Demographic, health & health behavior correlates of cognitive function (aggregate score, memory score, & mental status score) are reported.

Personnes Agees QUID (PAQUID)

o MMSE, Benton Visual Retention Test, Paired-associates test of WMS, Isaacs Set Test, Digit Symbol Substitution Test, single item measure of subjective memory; dementia evaluation 3777 persons aged 65+ living in Gironde & Dordogne, France.

Fabrigoule C et al. (1998). Cognitive process in preclinical phase of dementia.

Dartigues JF et al. (1997) Cognitive predictors of dementia in elderly community residents.

Jacqmin-Gadda H et al. (1997). A 5-yr longitudinal study of the Mini-Mental State Examination in normal aging.

Fabrigoule C et al. (1995) Social and leisure activities and risk of dementia: A prospective longitudinal study.

Gagnon M, Dartigues JF et al. (1994) Self-reported memory complaints and memory performance in elderly French community residents: Results of the PAQUID research program. Neuroepidemiology.

Dartigues JF et al. (1992). Principal lifetime occupation and cognitive impairment in a French elderly cohort.

Dartigues JF et al. (1992). Occupation during life and memory performance in nondemented French elderly community residents.

Monongahela Valley Independent Elders Survey (MoVIES Project; Ganguli et al., 1991, 1993, 1997)

o CERAD battery; Clock drawing; Trail Making Test

1366 subjects aged 65 and older followed every two years.

Chen, Ganguli et al. (1999) The temporal relationship between depressive symptoms and dementia. In this cohort, depressive symptoms appeared to be early manifestations rather than predictors of AD.

Mendelsohn et al. (1998). Use of antioxidant supplements and its association with cognitive function in a rural elderly cohort: the MoVIES Project. Monongahela Valley Independent Elders Survey.

Rotterdam Scan Study.

o Cohort of 1077 subjects, half of which overlaps with the Rotterdam Study. Has more detailed neuropsych testing

DeLeeuw, de Groot et al. (1999) A follow-up study of blood pressure and cerebral white matter lesions.

de Groot, de Leeuw et al. (2000). Cerebral white matter lesions and cognitive function: The Rotterdam Scan Study.

de Groot, de Leeuw et al. Cerebral white matter lesions and depressive symptoms in elderly adults.

The Maastricht Aging Study (MAAS).

Jolles, van Boxtel, et al. (1998). The Maastricht Aging Study (MAAS). The longitudinal perspective of cognitive aging.